DESCRIPTION OF THE EFFECT OF 1-O-GALLOYL-2,3-HEXAHYDROXYPHENOIL-4,6-VALONEIL-B-D-GLUCOSE POLYPHENOLS ISOLATED FROM EUPHORBIA-PLANT SPECIES ON RECEPTOR-CONTROLLED СА2+-CHANNELS

Authors

  • F.Yu. Ahmedov Andijan State University, Uzbekistan
  • A.E. Zaynabiddinov Andijan State University, Uzbekistan
  • U.G. Gayipov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan
  • R.N. Raximov, Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan

Keywords:

1-O-galloyl-2, 3-hexahydroxydiphenoil-4, 6-valoneyl- β -D-glucose

Abstract

To date, the classification, synthesis / biotransformation, and broad-spectrum pharmacological activity of plant-derived polyphenols have been studied in detail by some researchers, and one of the potential sources of these polyphenols is the plant species Euphorbia. Depending on the structure of plants of the genus Euphorbia, the staff of the Institute of Bioorganic Chemistry of the Academy of Sciences of the Republic of Uzbekistan isolated a number of polyphenols with vasorelaxant effect, including 1-O-galloyl-2,3-hexahydroxydiphenoil-4,6-valoneyl- β -D-glucose (PS-2 ) polyfnoli is one of them.

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References

Vazorelaxant Effect Of The PC-3 And PC-2 Polifenol Compounds Depending On Their Chemical Structure / Ahmedov F.Yu., Zaynаbiddinov A.E., Gayibov U.G., Yunusov L.S. // European Journal of Molecular & Clinical Medicine. – Scopus Indexed online journal. -2020. V. 7. (8). - Р. 1145-1155.

Influence of new polyphenol compound from Euphorbia plant on mitochondrial function / U.G. Gayibov, E.J. Komi_lov, R.N. Rakhimov, N.A. Ergashev [et al.] // Journal of Microbiology, Biotechnology and Food Sciences. – 2019. – № 8 (4). – P. 1021–1025.

Influence of valoneoyl groups on the interactions between Euphorbia tannins and human serum albumin / S. Sekow_ski, M. Bitiucki, M. Ionov, M. Zdeb [et al.] // Journal of Luminescence. – 2018. – № 194. – P. 170–178

Vasorelaxant and hypotensive effects of cheonwangbosimdan in SD and SHR rats / B. Kim, C. Jo, H-Y. Choi, K. Lee // Hindawi Evidence–Based Complementary and Alternative Medicine. – 2018. – № 1–8.

Rakhimov R.N., Abdullajanova N.G., Kamaev F.G. Phenolic compounds of Euphorbia canescens and E.franchetii // Chemistry of natural compounds. – 2011. – № 2. – P. 258–259.

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Published

2022-03-25

How to Cite

F.Yu. Ahmedov, A.E. Zaynabiddinov, U.G. Gayipov, & R.N. Raximov,. (2022). DESCRIPTION OF THE EFFECT OF 1-O-GALLOYL-2,3-HEXAHYDROXYPHENOIL-4,6-VALONEIL-B-D-GLUCOSE POLYPHENOLS ISOLATED FROM EUPHORBIA-PLANT SPECIES ON RECEPTOR-CONTROLLED СА2+-CHANNELS. International Scientific and Current Research Conferences, 1(01), 52–54. Retrieved from https://orientalpublication.com/index.php/iscrc/article/view/459

Issue

INNOVATIVE DEVELOPMENT OF MODERN SCIENCE: THEORY, METHODOLOGY, PRACTICE

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Articles

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Copyright (c) 2022 F.Yu. Ahmedov , A.E. Zaynabiddinov, U.G. Gayipov, R.N. Raximov,

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