Study Of The Analgesic Activity Of 1- (4ˊ-Dimethylaminophenyl -) - 6, 7 -Methylenedioxy-1,2,3,4- Tetrahydroisoquinoline

Authors

  • Jumadilla Rejepov Candidate of Medical Sciences Department of Pharmacology and Toxicology Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of Uzbekistan
  • Khilola Rakhmanova PhD Student Department of Pharmacology and Toxicology Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of Uzbekistan
  • Azizbek Azamatov Junior researcher Department of Pharmacology and Toxicology Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of Uzbekistan
  • Dilfuza Saidkhodjaeva Junior researcher Department of Pharmacology and Toxicology Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of Uzbekistan

Keywords:

1-(4ˊ-Dimethylaminophenyl -) - 6,, 7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline,

Abstract

The analgesic activity of a new compound 1- (4ˊ-Dimethylaminophenyl -) - 6,7-methylenedioxy-1,2,3,4
tetrahydroisoquinoline was studied under conditions of thermal and chemical irritation on the
models “hot plate test”, “acetic writhing”. As a result of the studies carried out, it was found that
the researching substance in various doses has an analgesic effect.

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References

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Zhumaev I.Z., Usmanov P.B. Synthesis

of 1-aryl-6,7-dimethoxy-1,2,3,4-

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of derivatives // Reports of the Academy

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Djurakulov Sh.N., Vinogradova V.I.,

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methylenedioxy-1,2,3,4

tetrahydroisoquinoline, exhibiting local

anesthetic, analgesic and antiarrhythmic

effects. Patent application No. IAP 2019.

Rejepov Jumadilla, Rakhmanova Hilola,

Azamatov Aziz “Toxicity and antiarrhythmic activity 1-(4-

Dimethylaminophenyl

dimethylaminophenyl)-6,7-dimethoxe1,2,3,4 tetrahydroisoquinoline”// The

American journal of medical sciences

and pharmaceutical research 2020 -p.

-133.

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Published

2020-12-10

How to Cite

Jumadilla Rejepov, Khilola Rakhmanova, Azizbek Azamatov, & Dilfuza Saidkhodjaeva. (2020). Study Of The Analgesic Activity Of 1- (4ˊ-Dimethylaminophenyl -) - 6, 7 -Methylenedioxy-1,2,3,4- Tetrahydroisoquinoline. International Scientific and Current Research Conferences, 1(1), 39–41. Retrieved from https://orientalpublication.com/index.php/iscrc/article/view/345

Issue

CONTEMPORARY SCIENTIFIC RESEARCH: CURRENT ISSUES, ACHIEVEMENTS AND INNOVATIONS

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Articles

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Copyright (c) 2020 Jumadilla Rejepov, Khilola Rakhmanova, Azizbek Azamatov, Dilfuza Saidkhodjaeva

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