CHANGES IN CLINICAL AND IMMUNOLOGICAL PARAMETERS DEPENDING ON THE SEVERITY OF COVID-19
Abstract
Coronavirus infection (COVID-19) is an acute infectious disease caused by a new strain of the SARS CoV-2 coronavirus with an aerosol droplet and contact-household transmission mechanism. Pathogenetically, COVID-19t is characterized by viremia, local and systemic immune-inflammatory processes, endotheliopathy, hyperactivity of the coagulation cascade, which can lead to the development of micro-macrothrombosis and hypoxia.
In this study, we examined 141 patients diagnosed with Covid-19 with moderate and severe course and checked immunological tests and laboratory tests as a coagulogram, a general blood test. The results obtained were processed by a statistical method. And revealed by interleukins and laboratory data correlations in various forms.
Keywords
COVID-19, cytokines, immunology, stages of COVID-19How to Cite
References
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. (2020) 395:497–506. doi: 10.1016/S0140-67362030183-5
WHO. Coronavirus disease 2019 (COVID-19) Situation Report 127. (2020). Available online at: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200526-covid-19-sitrep-127.pdf?sfvrsn$=$7b6655ab_8 (accessed May 27, 2020)
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Copyright (c) 2021 Nodirjon Ruzimurodov
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