CHANGES IN CLINICAL AND IMMUNOLOGICAL PARAMETERS DEPENDING ON THE SEVERITY OF COVID-19

Authors

  • Nodirjon Ruzimurodov Institute of Immunology and human genomics of the Academy of science of the Republic of Uzbekistan, Tashkent, Uzbekistan

Keywords:

COVID-19, cytokines, immunology, stages of COVID-19

Abstract

Coronavirus infection (COVID-19) is an acute infectious disease caused by a new strain of the SARS CoV-2 coronavirus with an aerosol droplet and contact-household transmission mechanism. Pathogenetically, COVID-19t is characterized by viremia, local and systemic immune-inflammatory processes, endotheliopathy, hyperactivity of the coagulation cascade, which can lead to the development of micro-macrothrombosis and hypoxia.

In this study, we examined 141 patients diagnosed with Covid-19 with moderate and severe course and checked immunological tests and laboratory tests as a coagulogram, a general blood test. The results obtained were processed by a statistical method. And revealed by interleukins and laboratory data correlations in various forms.

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References

Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. (2020) 395:497–506. doi: 10.1016/S0140-67362030183-5

WHO. Coronavirus disease 2019 (COVID-19) Situation Report 127. (2020). Available online at: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200526-covid-19-sitrep-127.pdf?sfvrsn$=$7b6655ab_8 (accessed May 27, 2020)

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Published

2021-11-11

How to Cite

Nodirjon Ruzimurodov. (2021). CHANGES IN CLINICAL AND IMMUNOLOGICAL PARAMETERS DEPENDING ON THE SEVERITY OF COVID-19. International Scientific and Current Research Conferences, 1(01), 1–3. Retrieved from https://orientalpublication.com/index.php/iscrc/article/view/137