BACTERIOPHAGES AS A SOLUTION TO THE PROBLEM OF ANTIBIOTIC RESISTANCE IN BACTERIAL INFECTIONS
Keywords:
Bacteriophages, multidrug resistance, antibioticsAbstract
From year to year, the problem of multi-resistance of microorganisms against antibacterial drugs is becoming more acute, which in turn prompts pharmaceutical companies to search for new compounds that are a temporary delay in the approaching crisis, as evidenced by a large multi-center study [1]. Bacteriophages are a promising tool in the fight against multi-resistant infections, although the assertion of the powerful antibacterial properties of bacteriophages causes controversy among the medical community, which prompted the interest of the authors of this article in an in-depth study of this issue.
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L Murray C.J, Ikuta K.S., Sharara F., Swetschinski L., Aguilar G.R., et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. VOLUME 399, ISSUE 10325, P629-655, FEBRUARY 12, 2022. Authia Gray DOI: https://doi.org/10.1016/S0140-6736(21)02724-0 © 2021 The Author(s). Published by Elsevier Ltd.
Parshin D.S. , Topchiev M.A., Pyatakov S.N. , Badma-Goryaev O.V., Kupriyanov A.V., Alibekov R.S.; Results of phage therapy for infectious complications in abdominal surgery; UDC: 617.55-089-06:576.858.9 DOI: 10.37279/2070-8092-2022-25-2-72-80;
Rubalskii E., Ruemke S., Salmoukas C., Erin C. Boyle, Warnecke G., Todorache I. et al. Bacteriophage therapy for critical infections related to cardiothoracic surgery //Antibiotics. – 2020. – Т. 9. – №. 5. – С. 232
Jault P., Leclerc T., Jennes S., Pirnay J.P., Que Y.A., Resch G., et al. Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial. Lancet Infect Dis. 2019;19(1):35-45. DOI: 10.1016/S1473-3099(18)30482-1
Fedorov E.A., Kretien S.O., Samokhin A.G., Tikunova N.V., Korytkin A.A., Pavlov V.V.. Short-term results of treatment of staphylococcal periprosthetic hip joint infection with combined antibiotics and bacteriophages treatment. Actabiomedicascientifica. 2021; 6(4): 50-63. doi: 10.29413/ABS.2021-6.4.5
Baytileuov T. A., Yakupbaeva K. Kh., Sadykov N. K. Antibacterial therapy in the treatment of infected pancreatic necrosis // Bulletin of surgery of Kazakhstan. – 2010. – No. 2 (22). - P. 14
Salmina T. A., Tsygipalo A. I., Skoda A. S. Experience of using polyvalent purified pyobacteriophage for the treatment of purulent wounds with long-term and ineffective treatment with antibacterial drugs // Difficult Patient. – 2016. – T. 14. – No. 10-11. – pp. 23-29.
Baimatov R. A., Nuruzova Z. A. Species characteristics and antibiotic resistance of pathogens of purulent-inflammatory diseases //Re-health journal. – 2019. – No. 3. – pp. 115-124.
Tashkhanova D. Ya., Nurmatova N. F. Analysis of the distribution of antibiotic-resistant bacteria in the Republic of Uzbekistan // Pediatrician. – 2017. – T. 8.
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Copyright (c) 2023 K.S. Rizaev, D.B.Tulyaganov, A.K. Sodikov

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